R. R. Khairullina, L. U. Dzhemileva, V. A. D'yakonov, A. G. Ibragimov, U. M. Dzhemilev, “Synthesis of 1,4,2,6-dithiadiazinane 1,1-dioxide and study of its cytotoxic activity”, Mendeleev Commun., 32:2 (2022), 178

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Mendeleev Communications, 2022, Volume 32, Issue 2, Pages 178–179
DOI: https://doi.org/10.1016/j.mencom.2022.03.008 (Mi mendc605)

This article is cited in 1 scientific paper (total in 1 paper)

Communications

Synthesis of 1,4,2,6-dithiadiazinane 1,1-dioxide and study of its cytotoxic activity

R. R. Khairullina, L. U. Dzhemileva, V. A. D'yakonov, A. G. Ibragimov, U. M. Dzhemilev

Institute of Petrochemistry and Catalysis, Ufa Federal Research Centre of the Russian Academy of Sciences, Ufa, Russian Federation

Full-text PDF (404 kB) Citations (1) Supplementary materials

DOI: https://doi.org/10.1016/j.mencom.2022.03.008

Graphic abstract: Synthesis of 1,4,2,6-dithiadiazinane 1,1-dioxide and study of its cytotoxic activity

Abstract: Cyclothiomethylation of sulfamide using paraformaldehyde or bis(dimethylamino)methane, hydrogen sulfide or its sodium salts catalyzed by rare-earth salts affords 1,4,2,6-dithiadi azinane 1,1-dioxide. The heterocycle was found to exhibit a pronounced cytotoxic effect against suspension tumor cell lines (Jurkat, HL60, K562, and U937).

Keywords: Cyclothiomethylation, Sulfamide, Catalysis, Hydrogen sulfide, Sodium sulfide, Samarium compounds, Ytterbium compounds, 1,4,2,6-Dithiadiazinane 1, 1-Dioxide, Cytotoxic activity.

Bibliographic databases:

Document Type: Article

Language: English

*Supplementary materials:*
		Supplementary_data_1.pdf	(1.0 Mb)

Citation: R. R. Khairullina, L. U. Dzhemileva, V. A. D'yakonov, A. G. Ibragimov, U. M. Dzhemilev, “Synthesis of 1,4,2,6-dithiadiazinane 1,1-dioxide and study of its cytotoxic activity”, Mendeleev Commun., 32:2 (2022), 178–179

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This publication is cited in the following 1 articles:

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