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Mendeleev Communications, 2022, Volume 32, Issue 3, Pages 354–356
DOI: https://doi.org/10.1016/j.mencom.2022.05.021
(Mi mendc662)
 

This article is cited in 5 scientific papers (total in 5 papers)

Communications

Synthesis and cytotoxicity of novel cholesterol–cobalt bis(dicarbollide) conjugates

A. A. Druzinaa, N. V. Dudarovaa, O. B. Zhidkovaa, I. A. Razumovb, O. I. Solovievab, V. V. Kanyginc, V. I. Bregadzea

a A.N. Nesmeyanov Institute of Organoelement Compounds of Russian Academy of Sciences, Moscow, Russian Federation
b Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russian Federation
c Novosibirsk State University, Novosibirsk, Russian Federation
Abstract: The novel conjugates of cholesterol with cobalt – bis(dicarbollide) were synthesized by the ring-opening reactions of the cyclic oxonium derivatives of [3,3′-Co(C2B9H11)2] with the OH group of cholesterol 2-hydroxyethyl ether. The compounds obtained were tested for toxicity to glioblastoma U-87 MG cells and human embryo fibroblasts FECH-15 cells
Keywords: boron neutron capture therapy, cancer, boron cage, cobalt bis(dicarbollide), cholesterol, liposomes, lipids, cytotoxicity, human glioblastoma U-87 MG.
Bibliographic databases:
Document Type: Article
Language: English
Supplementary materials:
Supplementary_data_1.pdf (1.1 Mb)


Citation: A. A. Druzina, N. V. Dudarova, O. B. Zhidkova, I. A. Razumov, O. I. Solovieva, V. V. Kanygin, V. I. Bregadze, “Synthesis and cytotoxicity of novel cholesterol–cobalt bis(dicarbollide) conjugates”, Mendeleev Commun., 32:3 (2022), 354–356
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  • This publication is cited in the following 5 articles:
    Citing articles in Google Scholar: Russian citations, English citations
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