Abstract:
An efficient selective C(3)–H arylation of furan ring in 2-(furan-2-yl)benzimidazoles, derivatives of fuberidazole fungicide, with aryl bromides catalyzed by [RuCl2(cymene)]2/ pivalic acid system has been accomplished. High selectivity of the process may be accounted for by the action of benzimidazol-2-yl substituent as the directing group.
Citation:
K. E. Shepelenko, K. A. Nikolaeva, I. G. Gnatiuk, O. G. Garanzha, A. A. Alexandrov, M. E. Minyaev, V. M. Chernyshev, “Ruthenium(II)-catalyzed C(3)–H arylation of furan moiety in fuberidazole derivatives”, Mendeleev Commun., 32:4 (2022), 485–487
Linking options:
https://www.mathnet.ru/eng/mendc702
https://www.mathnet.ru/eng/mendc/v32/i4/p485
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