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Mendeleev Communications, 2022, Volume 32, Issue 5, Pages 624–626
DOI: https://doi.org/10.1016/j.mencom.2022.09.018
(Mi mendc746)
 

This article is cited in 7 scientific papers (total in 7 papers)

Communications

Iron(iii) chloride-catalyzed mechanochemical cascade synthesis of highly-substituted pyrrolyl indoles

A. Mukherjeea, D. S. Kopchukab, S. Santraa, A. Majeec, G. V. Zyryanovab, O. N. Chupakhinab

a Institute of Chemical Engineering, Ural Federal University, Ekaterinburg, Russian Federation
b I.Ya. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences, Ekaterinburg, Russian Federation
c Department of Chemistry, Visva-Bharati University, Santiniketan, West Bengal, India
Abstract: Iron(iii) chloride has been found to serve as an efficient catalyst for a mechanochemical (ball milling) one-pot four- component cascade reaction of phenyl glyoxal, anilines, indoles and activated alkyne affording highly-substituted 3-(1H-pyrrol-2-yl)-1H-indoles. The procedure is beneficial because of mild conditions, easily available starting materials, cheap catalyst and possibility for scaling.
Keywords: ball milling, mechanochemical reactions, multicomponent reactions, cascade reactions, indoles, multi-substituted 3-(1H-pyrrol-2-yl)-1H-indoles, gram-scale synthesis.
Bibliographic databases:
Document Type: Article
Language: English
Supplementary materials:
Supplementary_data_1.pdf (1.1 Mb)


Citation: A. Mukherjee, D. S. Kopchuk, S. Santra, A. Majee, G. V. Zyryanov, O. N. Chupakhin, “Iron(iii) chloride-catalyzed mechanochemical cascade synthesis of highly-substituted pyrrolyl indoles”, Mendeleev Commun., 32:5 (2022), 624–626
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  • https://www.mathnet.ru/eng/mendc/v32/i5/p624
  • This publication is cited in the following 7 articles:
    Citing articles in Google Scholar: Russian citations, English citations
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