Abstract:
Ultrasound-mediated reaction of chitosan with ciprofloxacin in the presence of N,N'-dicyclohexylcarbodiimide in water gives the chitosan–ciprofloxacin conjugates of carboxamide type. The conjugates show a mediate antibacterial effect and reduced cytotoxicity.
Citation:
A. R. Egorov, M. N. Kurasova, O. Khubiev, N. A. Bogdanov, A. G. Tskhovrebov, A. A. Kirichuk, V. N. Khrustalev, V. V. Rubanik, V. V. Rubanik, A. S. Kritchenkov, “Ciprofloxacin chitosan conjugate: combined antibacterial effect and low toxicity”, Mendeleev Commun., 32:6 (2022), 774–776
Linking options:
https://www.mathnet.ru/eng/mendc795
https://www.mathnet.ru/eng/mendc/v32/i6/p774
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