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Mendeleev Communications, 2024, Volume 34, Issue 2, Pages 198–200
DOI: https://doi.org/10.1016/j.mencom.2024.02.012
(Mi mendc81)
 

This article is cited in 1 scientific paper (total in 1 paper)

Communications

Synthesis of furo[2,3-c]quinolinones via intramolecular C(3)–H arylation of furan core under Pd/NHC-catalysis

K. E. Shepelenkoa, I. G. Gnatiuka, M. E. Minyaevb, V. M. Chernysheva

a Platov South-Russian State Polytechnic University, Novocherkassk, Russian Federation
b N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russian Federation
Abstract: An efficient procedure for the preparation of furo[2,3-c]-quinolin-4(5H)-ones from 2-furoic acid N-(o-bromoaryl)- amides via selective intramolecular C(3)–H arylation of the furan nucleus involves the catalysis by a Pd/NHC system generated in situ from Pd(OAc)2 and readily available IPrSPh HCl proligand. A series of novel furo[2,3-c]quinolin-4(5H)-ones were prepared in 65–80% isolated yields.
Keywords: palladium, C–H activation, arylation, N-heterocyclic carbene ligands, furo[2,3-c]quinolin-4(5H)-ones.
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Document Type: Article
Language: English
Supplementary materials:
Supplementary_data_1.pdf (3.9 Mb)


Citation: K. E. Shepelenko, I. G. Gnatiuk, M. E. Minyaev, V. M. Chernyshev, “Synthesis of furo[2,3-c]quinolinones via intramolecular C(3)–H arylation of furan core under Pd/NHC-catalysis”, Mendeleev Commun., 34:2 (2024), 198–200
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  • This publication is cited in the following 1 articles:
    Citing articles in Google Scholar: Russian citations, English citations
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