Ph. T. Tham, Ph. T. Chinh, N. V. Tuyen, D. N. Bang, D. T. Van, V. T. Kien, H. T. Thanh, D. H. Quynh, V. D. Cuong, N. H. Thanh, A. P. Encabo, “Synthesis and cytotoxic evaluation of novel simplified plinabulin-quinoline derivatives”, Mendeleev Commun., 31:2 (2021), 213

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Mendeleev Communications, 2021, Volume 31, Issue 2, Pages 213–215
DOI: https://doi.org/10.1016/j.mencom.2021.03.022 (Mi mendc882)

This article is cited in 5 scientific papers (total in 5 papers)

Communications

Synthesis and cytotoxic evaluation of novel simplified plinabulin-quinoline derivatives

Ph. T. Tham^a, Ph. T. Chinh^b, N. V. Tuyen^c, D. N. Bang^b, D. T. Van^bd, V. T. Kien^b, H. T. Thanh^b, D. H. Quynh^bc, V. D. Cuong^be, N. H. Thanh^bc, A. P. Encabo^f

^a Hanoi University of Industry, Cau Dien, Bac Tu Liem, Hanoi, Vietnam
^b Thai Nguyen University of Science, Tan Thinh, Thai Nguyen, Vietnam
^c Institute of Chemistry, Vietnam Academy of Science and Technology, Hanoi, Vietnam
^d Thai Nguyen University of Education, Luong Ngoc Quyen, Thai Nguyen, Vietnam
^e Viet Tri University of Industry, Viet Tri, Phu Tho, Vietnam
^f Department of Chemistry, University of Valladolid, Valladolid, Spain

Full-text PDF (212 kB) Citations (5) Supplementary materials

DOI: https://doi.org/10.1016/j.mencom.2021.03.022

Graphic abstract: Synthesis and cytotoxic evaluation of novel simplified plinabulin-quinoline derivatives

Abstract: A series of new plinabulin-quinoline derivatives and their simplified analogues was obtained from N,N′-diacetyl-2,5- diketopiperazines utilizing its aldol condensation with benzaldehydes. One compound showed strong activity related to three (KB, HepG2 and Lu) cancer cell lines while two other compounds demonstrated high potencies against breast carcinoma cell line (MCF-7).

Keywords: plinabulin, quinoline, piperazine-2,5-diones, anticancer, cytotoxicity.

Bibliographic databases:

Document Type: Article

Language: English

*Supplementary materials:*
		Supplementary_data_1.pdf	(5.7 Mb)

Citation: Ph. T. Tham, Ph. T. Chinh, N. V. Tuyen, D. N. Bang, D. T. Van, V. T. Kien, H. T. Thanh, D. H. Quynh, V. D. Cuong, N. H. Thanh, A. P. Encabo, “Synthesis and cytotoxic evaluation of novel simplified plinabulin-quinoline derivatives”, Mendeleev Commun., 31:2 (2021), 213–215

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https://www.mathnet.ru/eng/mendc/v31/i2/p213

This publication is cited in the following 5 articles:

Citing articles in Google Scholar: Russian citations, English citations
Related articles in Google Scholar: Russian articles, English articles

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