Ya. Yu. Shmoylova, Yu. A. Kovygin, I. V. Ledenyova, M. A. Prezent, E. D. Daeva, S. V. Baranin, Kh. S. Shikhaliev, “An efficient synthesis of new polyfunctional hexahydro pyrido[1,2-a]pyrazin-1-ones”, Mendeleev Commun., 31:2 (2021), 259

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Mendeleev Communications, 2021, Volume 31, Issue 2, Pages 259–261
DOI: https://doi.org/10.1016/j.mencom.2021.03.039 (Mi mendc899)

This article is cited in 4 scientific papers (total in 4 papers)

Communications

An efficient synthesis of new polyfunctional hexahydro pyrido[1,2-a]pyrazin-1-ones

Ya. Yu. Shmoylova^a, Yu. A. Kovygin^a, I. V. Ledenyova^a, M. A. Prezent^b, E. D. Daeva^b, S. V. Baranin^b, Kh. S. Shikhaliev^a

^a Department of Chemistry, Voronezh State University, Voronezh, Russian Federation
^b N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russian Federation

Full-text PDF (202 kB) Citations (4) Supplementary materials

DOI: https://doi.org/10.1016/j.mencom.2021.03.039

Graphic abstract: An efficient synthesis of new polyfunctional hexahydro pyrido[1,2-<i>a</i>]pyrazin-1-ones

Abstract: New polyfunctional hydrogenated pyrido[1,2-a]pyrazin- 1-ones were obtained by regioselective recyclization of N-arylitaconimides with alkyl (3-oxopiperazin-2-ylidene)acetates. The supposed cascade reaction pathway involves the Michael addition of the nucleophile to an activated double bond and subsequent intramolecular transamidation of the intermediate with simultaneous recycling.

Keywords: pyrido[1,2-a]pyrazin-1-ones, N-arylitaconimides, alkyl (3-oxopiperazin-2-ylidene)acetates, recyclization, microwave irradiation.

Bibliographic databases:

Document Type: Article

Language: English

*Supplementary materials:*
		Supplementary_data_1.pdf	(2.1 Mb)

Citation: Ya. Yu. Shmoylova, Yu. A. Kovygin, I. V. Ledenyova, M. A. Prezent, E. D. Daeva, S. V. Baranin, Kh. S. Shikhaliev, “An efficient synthesis of new polyfunctional hexahydro pyrido[1,2-a]pyrazin-1-ones”, Mendeleev Commun., 31:2 (2021), 259–261

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https://www.mathnet.ru/eng/mendc899

https://www.mathnet.ru/eng/mendc/v31/i2/p259

This publication is cited in the following 4 articles:

Citing articles in Google Scholar: Russian citations, English citations
Related articles in Google Scholar: Russian articles, English articles

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