A. V. Evdokimova, A. A. Alexeev, E. V. Nurieva, E. R. Milaeva, S. A. Kuznetsov, O. N. Zefirova, “N-(4-Methoxyphenyl)-substituted bicyclic isothioureas: effect on morphology of cancer cells”, Mendeleev Commun., 31:3 (2021), 288

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Mendeleev Communications, 2021, Volume 31, Issue 3, Pages 288–290
DOI: https://doi.org/10.1016/j.mencom.2021.04.003 (Mi mendc907)

This article is cited in 6 scientific papers (total in 6 papers)

Communications

N-(4-Methoxyphenyl)-substituted bicyclic isothioureas: effect on morphology of cancer cells

A. V. Evdokimova^a, A. A. Alexeev^a, E. V. Nurieva^a, E. R. Milaeva^ab, S. A. Kuznetsov^c, O. N. Zefirova^ab

^a Department of Chemistry, M.V. Lomonosov Moscow State University, Moscow, Russian Federation
^b Institute of Physiologically Active Compounds, Federal Research Center of Problems of Chemical Physics and Medicinal Chemistry, Russian Academy of Sciences, Chernogolovka, Moscow Region, Russian Federation
^c Institute of Biological Sciences, Cell Biology and Biosystems Technology, University of Rostock, Rostock, Germany

Full-text PDF (335 kB) Citations (6) Supplementary materials

DOI: https://doi.org/10.1016/j.mencom.2021.04.003

Graphic abstract: <i>N</i>-(4-Methoxyphenyl)-substituted bicyclic isothioureas: effect on morphology of cancer cells

Abstract: Bicyclic isothioureas of N-(4-methoxyphenyl)-2-aminocycloalkane[d]thiazole type were obtained using intramolecular electrophilic cyclization of N-(cycloalk-2-enyl)-N′-(4-methoxyphenyl)thioureas. Isothiourea fused with sevenmembered ring caused noticeable changes of the morphology of human lung carcinoma cells A549, but without affecting their microtubule net.

Keywords: thiazolin-2-amines, cycloalka[d]thiazoles, thioureas, isothioureas, heterocyclization, verubulin, lung carcinoma A549, cancer cell morphology.

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Document Type: Article

Language: English

*Supplementary materials:*
		Supplementary_data_1.pdf	(1.5 Mb)

Citation: A. V. Evdokimova, A. A. Alexeev, E. V. Nurieva, E. R. Milaeva, S. A. Kuznetsov, O. N. Zefirova, “N-(4-Methoxyphenyl)-substituted bicyclic isothioureas: effect on morphology of cancer cells”, Mendeleev Commun., 31:3 (2021), 288–290

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https://www.mathnet.ru/eng/mendc907

https://www.mathnet.ru/eng/mendc/v31/i3/p288

This publication is cited in the following 6 articles:

Citing articles in Google Scholar: Russian citations, English citations
Related articles in Google Scholar: Russian articles, English articles

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