Abstract:
New 2,8-di(het)aryl-containing dioxadecaazadicyclopenta[e,l]pyrenes, furazan-annulated polyaza polycycles, have been synthesized by acid-catalyzed cyclocondensation of difurazanotetraazadecalin with formaldehyde and primary (het)arylamines. The cytotoxic activity of these compounds against tumor cell lines (Jurkat, K562, U937, HL60) has been estimated.
Citation:
E. B. Rakhimova, V. Yu. Kirsanov, E. S. Meshcheryakova, L. U. Dzhemileva, V. A. D'yakonov, A. G. Ibragimov, U. M. Dzhemilev, “Synthesis and cytotoxic activity of new annulated furazan derivatives”, Mendeleev Commun., 31:3 (2021), 362–364
Linking options:
https://www.mathnet.ru/eng/mendc930
https://www.mathnet.ru/eng/mendc/v31/i3/p362
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