Abstract:
Novel tris(4-alkylaminopyridin-1-ium) trichlorides with alkylcyanuric spacer were synthesized by quaternization of 4-alkylaminopyridines with tris(2-chloroethyl) cyanurate. The obtained compounds were evaluated for microbiological activity against five pathogenic bacterial strains (Escherichia coli, Klebsiella pneumoniae, Staphylococcus aureus, Acinobacter baumannii, Pseudomonas aeruginosa). The results indicate the presence of pronounced antibacterial properties in this group of compounds.
Citation:
A. N. Vereshchagin, N. A. Frolov, A. P. Minaeva, E. V. Detusheva, Ya. V. Derkach, M. P. Egorov, “Synthesis and biological evaluation of novel cyanuric acid-tethered tris-pyridinium derivatives”, Mendeleev Commun., 31:3 (2021), 368–369
Linking options:
https://www.mathnet.ru/eng/mendc932
https://www.mathnet.ru/eng/mendc/v31/i3/p368
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