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Mendeleev Communications, 2021, Volume 31, Issue 3, Pages 368–369
DOI: https://doi.org/10.1016/j.mencom.2021.04.028
(Mi mendc932)
 

This article is cited in 13 scientific papers (total in 13 papers)

Communications

Synthesis and biological evaluation of novel cyanuric acid-tethered tris-pyridinium derivatives

A. N. Vereshchagina, N. A. Frolova, A. P. Minaevaab, E. V. Detushevac, Ya. V. Derkachab, M. P. Egorova

a N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russian Federation
b D.Mendeleev University of Chemical Technology of Russia, Moscow, Russian Federation
c State Research Center for Applied Microbiology & Biotechnology, Obolensk, Moscow Region, Russian Federation
Abstract: Novel tris(4-alkylaminopyridin-1-ium) trichlorides with alkylcyanuric spacer were synthesized by quaternization of 4-alkylaminopyridines with tris(2-chloroethyl) cyanurate. The obtained compounds were evaluated for microbiological activity against five pathogenic bacterial strains (Escherichia coli, Klebsiella pneumoniae, Staphylococcus aureus, Acinobacter baumannii, Pseudomonas aeruginosa). The results indicate the presence of pronounced antibacterial properties in this group of compounds.
Keywords: tris-quaternary ammonium compounds, pyridinium salts, biological activity, antibacterial agents.
Bibliographic databases:
Document Type: Article
Language: English
Supplementary materials:
Supplementary_data_1.pdf (2.0 Mb)


Citation: A. N. Vereshchagin, N. A. Frolov, A. P. Minaeva, E. V. Detusheva, Ya. V. Derkach, M. P. Egorov, “Synthesis and biological evaluation of novel cyanuric acid-tethered tris-pyridinium derivatives”, Mendeleev Commun., 31:3 (2021), 368–369
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  • https://www.mathnet.ru/eng/mendc/v31/i3/p368
  • This publication is cited in the following 13 articles:
    Citing articles in Google Scholar: Russian citations, English citations
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