E. V. Kuznetsova, K. T. Kalinin, N. G. Sedush, A. A. Nazarov, D. S. Volkov, S. N. Chvalun, “Structure and cytotoxicity of biodegradable poly(d,l-lactide-co-glycolide) nanoparticles loaded with oxaliplatin”, Mendeleev Commun., 31:4 (2021), 512

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Mendeleev Communications, 2021, Volume 31, Issue 4, Pages 512–514
DOI: https://doi.org/10.1016/j.mencom.2021.07.025 (Mi mendc973)

This article is cited in 15 scientific papers (total in 15 papers)

Communications

Structure and cytotoxicity of biodegradable poly(d,l-lactide-co-glycolide) nanoparticles loaded with oxaliplatin

E. V. Kuznetsova^a, K. T. Kalinin^a, N. G. Sedush^a, A. A. Nazarov^b, D. S. Volkov^b, S. N. Chvalun^ac

^a National Research Centre 'Kurchatov Institute', Moscow, Russian Federation
^b Department of Chemistry, M.V. Lomonosov Moscow State University, Moscow, Russian Federation
^c N.S. Enikolopov Institute of Synthetic Polymeric Materials, Russian Academy of Sciences, Moscow, Russian Federation

Full-text PDF (487 kB) Citations (15) Supplementary materials

DOI: https://doi.org/10.1016/j.mencom.2021.07.025

Graphic abstract: Structure and cytotoxicity of biodegradable poly(d,l-lactide-<i>co</i>-glycolide) nanoparticles loaded with oxaliplatin

Abstract: Spherical nanoparticles based on the biocompatible and biodegradable poly(d,l-lactide-co-glycolide) copolymer (90 : 10) loaded with oxaliplatin were produced by nanoprecipitation. Effect of the oxaliplatin loading on structure, size and morphology of the copolymer particles is considered. The nanoformulation of oxaliplatin demonstrates enhanced cytotoxicity and selectivity in vitro against several cancer cells compared with the free drug.

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Document Type: Article

Language: English

*Supplementary materials:*
		Supplementary_data_1.pdf	(687.9 Kb)

Citation: E. V. Kuznetsova, K. T. Kalinin, N. G. Sedush, A. A. Nazarov, D. S. Volkov, S. N. Chvalun, “Structure and cytotoxicity of biodegradable poly(d,l-lactide-co-glycolide) nanoparticles loaded with oxaliplatin”, Mendeleev Commun., 31:4 (2021), 512–514

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https://www.mathnet.ru/eng/mendc/v31/i4/p512

This publication is cited in the following 15 articles:

Citing articles in Google Scholar: Russian citations, English citations
Related articles in Google Scholar: Russian articles, English articles

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