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Nanosystems: Physics, Chemistry, Mathematics, 2024, Volume 15, Issue 6, Pages 921–935
DOI: https://doi.org/10.17586/2220-8054-2024-15-6-921-935
(Mi nano1336)
 

CHEMISTRY AND MATERIAL SCIENCE

Biomedical applications of graphene-based nanomaterials in gene delivery, tissue engineering, biosensing and for the development antibacterial agents

Konstantin N. Semenovabc, Sergei V. Ageevab, Olga S. Shemchukac, Gleb O. Iurevac, Abdelsattar O. E. Abdelhalimd, Igor V. Murinb, Pavel K. Kozhukhova, Anastasia V. Penkovab, Dmitriy N. Maystrenkoc, Oleg E. Molchanovc, Vladimir V. Sharoykoacb

a Pavlov First St. Petersburg State Medical University, St. Petersburg, Russia
b St. Petersburg State University, St. Petersburg, Russia
c A. M. Granov Russian Research Centre for Radiology and Surgical Technologies, St. Petersburg, Russia
d Environmental Research Department, National Centre for Social and Criminological Research (NCSCR), Giza, Egypt
Abstract: Graphene and graphene oxide have emerged as promising materials in various biomedical applications due to their unique physicochemical properties. This review provides a comprehensive overview of their utilization in gene delivery, tissue engineering, biosensors and antibacterial and antimicrobial agents. In gene delivery, graphene-based materials offer efficient delivery platforms with enhanced cellular uptake and minimal cytotoxicity, promising advancements in gene therapy. Additionally, in tissue engineering, graphene and graphene oxide scaffolds exhibit excellent biocompatibility, electrical conductivity, and mechanical properties, facilitating cell adhesion, proliferation, and differentiation for tissue regeneration. Moreover, graphenebased biosensors demonstrate high sensitivity, selectivity, and stability, enabling rapid and accurate detection of biomolecules for diagnostic and therapeutic purposes. This review highlights the recent advancements, challenges, and future prospects of graphene and graphene oxide in revolutionizing biomedical technologies, paving the way for innovative solutions in healthcare.
Keywords: graphene, graphene oxide, composites, nanostructures, biocompatibility, biomedical applications.
Funding agency Grant number
Saint Petersburg State University 11602266
The authors acknowledge St. Petersburg State University for a research project 11602266.
Received: 21.06.2024
Revised: 08.10.2024
Accepted: 07.11.2024
Bibliographic databases:
Document Type: Article
Language: English
Citation: Konstantin N. Semenov, Sergei V. Ageev, Olga S. Shemchuk, Gleb O. Iurev, Abdelsattar O. E. Abdelhalim, Igor V. Murin, Pavel K. Kozhukhov, Anastasia V. Penkova, Dmitriy N. Maystrenko, Oleg E. Molchanov, Vladimir V. Sharoyko, “Biomedical applications of graphene-based nanomaterials in gene delivery, tissue engineering, biosensing and for the development antibacterial agents”, Nanosystems: Physics, Chemistry, Mathematics, 15:6 (2024), 921–935
Citation in format AMSBIB
\Bibitem{SemAgeShe24}
\by Konstantin~N.~Semenov, Sergei~V.~Ageev, Olga~S.~Shemchuk, Gleb~O.~Iurev, Abdelsattar~O.~E.~Abdelhalim, Igor~V.~Murin, Pavel~K.~Kozhukhov, Anastasia~V.~Penkova, Dmitriy~N.~Maystrenko, Oleg~E.~Molchanov, Vladimir~V.~Sharoyko
\paper Biomedical applications of graphene-based nanomaterials in gene delivery, tissue engineering, biosensing and for the development antibacterial agents
\jour Nanosystems: Physics, Chemistry, Mathematics
\yr 2024
\vol 15
\issue 6
\pages 921--935
\mathnet{http://mi.mathnet.ru/nano1336}
\crossref{https://doi.org/10.17586/2220-8054-2024-15-6-921-935}
\elib{https://elibrary.ru/item.asp?id=79442917}
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