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Optics and Spectroscopy, 2022, Volume 130, Issue 6, Pages 918–923
DOI: https://doi.org/10.21883/OS.2022.06.52634.41-22 (Mi os1772) 		 
Proceedings of The XXV Annual International Conference "Saratov Fall Meeting 2021", September 27-October 1, 2021, Saratov, Russia
Biophotonics

Dielectric study of blood serum of patients with oncohematological diseases

R. A. Castroa, L. V. Plotnikovab, Zh. A. Salnikovaa, A. P. Smirnova, A. A. Kononova, O. S. Vezob, A. D. Garifullinc, A. Yu. Kuvshinovc, S. V. Voloshindce, A. M. Polyanichkobf

a Herzen State Pedagogical University of Russia, 191186 St. Petersburg, Russia
b Saint Petersburg State University, 199034 St. Petersburg, Russia
c Russian Scientific Research Institute of Hematology and Transfusiology, St. Petersburg, 191024, Russia, St. Petersburg
d Kirov Medical Force Academy, 194044 St. Petersburg, Russia
e North-Western State Medical University named after I.I. Mechnikov, 191015 St. Petersburg, Russia
f Institute of Cytology Russian Academy of Science, 194064 St. Petersburg, Russia
Full-text PDF (257 kB)
DOI: https://doi.org/10.21883/OS.2022.06.52634.41-22
Abstract: Features of charge transfer and dielectric relaxation processes in blood serum samples of patients with oncohematological diseases and healthy donors were investigated by dielectric spectroscopy method. The observed features of the dielectric spectra for donors and patients, namely the decrease in conductivity in the high frequency region, the correlation between the degree indicator s and the total protein content, as well as changes in the spectrum of relaxation complexes indicate a change in the quantitative ratios of blood components in the presence of disease. This system rearrangement is the result of the fact that conformation of proteins (albumins and immunoglobulins) for patients is change.
Keywords: dielectric spectroscopy, serum, chronic lymphocytic leukemia, multiple myeloma, charge transfer, dielectric relaxation.
Funding agency Grant number
Ministry of Science and Higher Education of the Russian Federation FSZN-2020-0026
The study was performed under the national task with financial support of Ministry of Education of Russia (project № FSZN-2020-0026).
Received: 30.03.2022
Revised: 08.04.2022
Accepted: 08.04.2022
Bibliographic databases:
Document Type: Article
Language: Russian
Citation: R. A. Castro, L. V. Plotnikova, Zh. A. Salnikova, A. P. Smirnov, A. A. Kononov, O. S. Vezo, A. D. Garifullin, A. Yu. Kuvshinov, S. V. Voloshin, A. M. Polyanichko, “Dielectric study of blood serum of patients with oncohematological diseases”, Optics and Spectroscopy, 130:6 (2022), 918–923
Citation in format AMSBIB
\Bibitem{CasPloSal22}
\by R.~A.~Castro, L.~V.~Plotnikova, Zh.~A.~Salnikova, A.~P.~Smirnov, A.~A.~Kononov, O.~S.~Vezo, A.~D.~Garifullin, A.~Yu.~Kuvshinov, S.~V.~Voloshin, A.~M.~Polyanichko
\paper Dielectric study of blood serum of patients with oncohematological diseases
\jour Optics and Spectroscopy
\yr 2022
\vol 130
\issue 6
\pages 918--923
\mathnet{http://mi.mathnet.ru/os1772}
\crossref{https://doi.org/10.21883/OS.2022.06.52634.41-22}
\elib{https://elibrary.ru/item.asp?id=49347632}
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