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This article is cited in 2 scientific papers (total in 2 papers)
Nanostructures
X-ray contrast properties of bismuth-based nanoformulations
M. S. Savinova, O. Griaznovaabc, G. V. Tikhonowskia, A. A. Popova, I. N. Zavestovskayad, S. M. Klimentova, A. V. Kabashine a National Research Nuclear University MEPhI, Institute for Physics and Engineering in Biomedicine, 115409, Moscow, Russia
b Skolkovo Institute of Science and Technology, Center for Photonic Science and Engineering, 121205, Moscow, Russia
c Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997, Moscow, Russia
d Lebedev Physical Institute, Russian Academy of Sciences, 119991, Moscow, Russia
e LP3, Aix Marseille University, CNRS, 13288 Marseille, France
Abstract:
The possibility of using elemental bismuth nanoparticles as sensitizers for radiation therapy and computed tomography contrast agents is investigated. A comparative analysis of the X-ray contrast properties of bismuth nanoparticles with classical gold nanoparticles and bismuth oxychloride nanosheets is carried out. It is shown that laser-synthesized bismuth nanoparticles demonstrate higher X-ray contrast efficiency compared to traditional gold nanoparticles; they also have X-ray contrast properties similar to those of chemically synthesized analogues based on bismuth oxychloride nanosheets. Unique physicochemical characteristics in combination with high radiopaque properties of laser-synthesized bismuth nanoparticles form a new promising alternative to traditional sensitizers for radiation theranostics of oncological diseases.
Keywords:
bismuth, nanoparticles, computed tomography, laser ablation in liquids, nanomedicine.
Received: 17.07.2023 Revised: 09.08.2023
Citation:
M. S. Savinov, O. Griaznova, G. V. Tikhonowski, A. A. Popov, I. N. Zavestovskaya, S. M. Klimentov, A. V. Kabashin, “X-ray contrast properties of bismuth-based nanoformulations”, Kvantovaya Elektronika, 53:7 (2023), 575–579 [Bull. Lebedev Physics Institute, 50:suppl. 11 (2023), S1265–S1271]
Linking options:
https://www.mathnet.ru/eng/qe18276 https://www.mathnet.ru/eng/qe/v53/i7/p575
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