Abstract:
Recent advances in the synthesis of macrocycles with musk scent via catalytic olefin metathesis are presented with a particular emphasis on advantages offered by the metathesis technology. The review includes short historical background about musks and olefin metathesis to introduce the subject. Substantial emphasis is given on ring-closing metathesis (RCM) as a tool for the synthesis of cyclic compounds such as civetone, muscone, egzaltolide, ambrettolide/isoambrettolide and yuzu lactone.
The bibliography includes 106 references.
Received: 06.12.2019
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Document Type:
Article
Language: English
Original paper language: English
Citation:
Adrian Sytniczuk, Mariusz Milewski, Anna Kajetanowicz, Karol Grela, “Preparation of macrocyclic musks via olefin metathesis: comparison with classical syntheses and recent advances”, Russian Chem. Reviews, 89:4 (2020), 469–490