Abstract:
Cyanomethyl-substituted tetrahydroisoquinolines and tetrahydrothieno[3,2-c]pyridines were synthesized by multicomponent reaction of the dihydro analogues of aforesaid systems with benzyne and acetonitrile. The products obtained relate to alkaloids of isoquinoline family of 1,2,3,4-tetrahydro level.
Citation:
N. I. Guranova, A. V. Varlamov, V. V. Ilyushenkova, E. A. Sokolova, T. N. Borisova, A. V. Aksenov, V. N. Khrustalev, L. G. Voskresenskii, “Reactions of 3,4-dihydroisoquinolines and dihydrothieno[3,2-c]pyridines with benzyne”, Mendeleev Commun., 27:5 (2017), 506–508
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https://www.mathnet.ru/eng/mendc2043
https://www.mathnet.ru/eng/mendc/v27/i5/p506
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