Abstract:
Novel class of multicomponent quinolone antibiotics,crystalline hydrogen peroxide adducts of nalidixic acid C12H12N2O3 · H2O2 and ciprofloxacin C17H18F1N3O3 · 5 H2O2, were prepared from highly concentrated hydrogen peroxide, and their structures were determined by X-ray crystallography. The second compound contains decameric H-bonded hydrogen peroxide clusters, which makes this substance one of the richest in hydrogen peroxide among organic peroxosolvates.
Citation:
M. A. Kiseleva, P. V. Prikhodchenko, A. V. Churakov, “Novel peroxosolvates of quinolone antibiotics containing large hydrogen peroxide clusters”, Mendeleev Commun., 34:1 (2024), 25–27
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https://www.mathnet.ru/eng/mendc33
https://www.mathnet.ru/eng/mendc/v34/i1/p25
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