P. Paramonova, T. Sharonova, S. A. Kalinin, E. G. Chupakhin, A. S. Bunev, M. Yu. Krasavin, “(E)-3-Arylidene-4-diazopyrrolidine-2,5-diones conveniently elaborated into cytotoxic compounds bearing primary sulfonamide and Michael acceptor moieties”, Mendeleev Commun., 32:2 (2022), 176

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Mendeleev Communications, 2022, Volume 32, Issue 2, Pages 176–177
DOI: https://doi.org/10.1016/j.mencom.2022.03.007 (Mi mendc604)

This article is cited in 3 scientific papers (total in 3 papers)

Communications

(E)-3-Arylidene-4-diazopyrrolidine-2,5-diones conveniently elaborated into cytotoxic compounds bearing primary sulfonamide and Michael acceptor moieties

P. Paramonova^a, T. Sharonova^a, S. A. Kalinin^ab, E. G. Chupakhin^ac, A. S. Bunev^b, M. Yu. Krasavin^ac

^a Institute of Chemistry, St. Petersburg State University, St. Petersburg, Russian Federation
^b Medicinal Chemistry Centre, Togliatti State University, Togliatti, Russian Federation
^c Immanuel Kant Baltic Federal University, Kaliningrad, Russian Federation

Full-text PDF (156 kB) Citations (3)

DOI: https://doi.org/10.1016/j.mencom.2022.03.007

Graphic abstract: (E)-3-Arylidene-4-diazopyrrolidine-2,5-diones conveniently elaborated into cytotoxic compounds bearing primary sulfonamide and Michael acceptor moieties

Abstract: The earlier described (E)-3-arylidene-4-diazopyrrolidine-2,5-diones have been elaborated into two distinct series of compounds both bearing a primary sulfonamide moiety and an electrophilic ‘Michael acceptor’ motif. These compounds demonstrated cytotoxicity against colorectal cancer cell line HCT 116.

Keywords: Rhodium catalysis, Diazo coupling, Sulfonamides, Michael acceptors, Enzyme inhibitors, MTT assay, Cell viability, Anti-proliferative agents.

Document Type: Article

Language: English

*Supplementary materials:*
		Supplementary_data_1.pdf	(2.3 Mb)

Citation: P. Paramonova, T. Sharonova, S. A. Kalinin, E. G. Chupakhin, A. S. Bunev, M. Yu. Krasavin, “(E)-3-Arylidene-4-diazopyrrolidine-2,5-diones conveniently elaborated into cytotoxic compounds bearing primary sulfonamide and Michael acceptor moieties”, Mendeleev Commun., 32:2 (2022), 176–177

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https://www.mathnet.ru/eng/mendc/v32/i2/p176

This publication is cited in the following 3 articles:

Citing articles in Google Scholar: Russian citations, English citations
Related articles in Google Scholar: Russian articles, English articles

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