Synthesis and structure of stereoisomers of 3,4-benzo-5,10-diphenyl-1,3-diaza-7-oxa-6-phosphabicyclo[4.3.1]decane-2,6-dione

A mild approach to the synthesis of the title cage aminophosphonate has been developed based on the intramolecular cyclization of 2-(2-benzylideneaminoethoxy)-1-phenylbenzo[e]-1,3,2-azaoxaphosphorin-4-one obtained from 1-phenyl-2-chlorobenzo[e]-1,3,2-azaoxaphosphorin-4-one and (2-benzylideneaminoethoxy)trimethylsilane. The structure of isolated diastereomers of the product was determined by NMR spectroscopy and single crystal X-ray diffraction analysis.