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Эта публикация цитируется в 4 научных статьях (всего в 4 статьях)
Increased dipeptoid diversity resulting from post-condensational manipulation of the Ugi reaction products
M. Yu. Krasavinab, M. M. Nikulnikovab
a Department of Organic Chemistry,
Chemical Diversity Research Institute, Khimki, Moscow Region, Russian Federation
b Science and Education Center “Innovative Research”, Yaroslavl State Pedagogical University, Yaroslavl, Russian Federation
Аннотация:
5,6-Dihydropyrazolo[1,5-a]pyrazines prepared via the Ugi reaction involving pyrazole-3-carboxylic convertible tert-butyl isocyanide and subsequent microwave-promoted cyclization, were found to be prone to opening with primary and secondary amines, thereby providing a facile, three-step access to a greater diversity of Ugi-type dipeptoids, some of which cannot be accessed via the Ugi reaction itself.
Ключевые слова:
isocyanide-based multicomponent reactions, post-Ugi modifications, acid pyrazolides, nucleophilic opening, convertible isocyanid.
Образец цитирования:
M. Yu. Krasavin, M. M. Nikulnikov, “Increased dipeptoid diversity resulting from post-condensational manipulation of the Ugi reaction products”, Mendeleev Commun., 22:1 (2012), 41–42
Образцы ссылок на эту страницу:
https://www.mathnet.ru/rus/mendc2732 https://www.mathnet.ru/rus/mendc/v22/i1/p41
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