Аннотация:
The Raman spectrum of a single erythrocyte captured by a microfluidic chip was recorded to determine the conformation of hemoglobin under conditions similar to the hemodynamics of a blood vessel. Amplitude changes in the Raman spectrum at 1355, 1375, 1552, 1620, 1585 and 1637 cm−1 reflect changes in pO2 due to O2 binding to hemoglobin heme.
Образец цитирования:
G. V. Grigorev, A. V. Lebedev, X. Wang, X. Qian, G. V. Maksimov, E. U. Parshina, L. Lin, “Hemoglobin conformation detection by Raman spectroscopy on single human red blood cells captured in a microfluidic chip”, Mendeleev Commun., 32:4 (2022), 504–506